Senior Member of Technical Staff (Applied AI)
Quick facts
- Pay
- $230,000 - $350,000
- Type
- Full-time
- Location
- New York City, NY
- Skills
- Python, Docker, AWS
- Industry
- Information Technology — 671 open jobs
- Visa in listing
- H-1B
- Apply
- Free to apply — never pay anyone for a job offer or visa sponsorship
Job description
Senior Member of Technical Staff (Applied AI) Location: New York City
Why You Should Join Us
Solstice is redefining how life sciences organizations commercialize therapeutics. We are building a commercial engine that allows pharmaceutical marketers to launch campaigns at 100x the speed. Our mission is to accelerate the knowledge of life-saving medicines.
Rapid growth: Over the past year, we have worked with some of the top life sciences manufacturers and over 50+ pharma brands including Pfizer and AstraZeneca.
A hard technical problem: We are trying to rethink the way the largest, most innovative therapies in the world come to market. Every claim in pharma marketing content must trace to an approved source. Fair balance rules govern placement. All materials go through rigorous medical, legal, and regulatory review, which can last months. Building persuasive and defensible content is a genuine challenge, with no playbook. We have the customers and proprietary data to do this right.
Top-tier investors: Our backers include Transformation Capital, Twelve Below, Virtue and the founders of Datavant, Commure, and Paradigm.
Influence and ownership: This senior role directly shapes our architectural future. We're seeking someone who wants responsibility, not someone who needs work handed to them.
About the Role
We're hiring a senior Applied AI engineer to own the technical direction of our AI systems: retrieval, generation, verification, evaluation, and keeping systems running in production. Nothing's predetermined. When there's a fork in the road, you decide. You will work closely with VP of Engineering Jay, and co-founders Aris and Yiwen, influencing product strategy, technical hiring, and our market positioning.
What You'll Be Working On
High-craft output: Our clients demand work with polish, not "AI slop." Pharma assets like emails, banners, slides and leave-behinds require both visual and textual excellence. ISI must be prominent, brand systems must endure, and hierarchy and typography must survive generation. Our job isn't just compliance. It's making sure assets don't get quietly rewritten by marketers.
Connecting content to outcomes: Passing MLR review means a piece can ship, but not that it worked. We'll connect generated assets to real-world performance, including engagement, HCP response and scripts written, and use that data to improve future output.
Evaluation where ground truth is slow: Determining compliance is slow, coming back as reviewer redlines in inconsistent formats. Developing offline metrics that track downstream MLR pass rate is critical.
Claim-level attribution: True grounding means every sentence can be traced back to a specific, defensible source. Our proprietary corpora span prescribing information, clinical data, approved assets, style guides and claim libraries, and provenance must be preserved through generation.
ML Ops and behavioral regression: Full CI/CD for ML, versioning, automated testing, monitoring, and the harder under-the-hood work. Upgrades shift output in ways easy stats can miss, and tail risks matter most. Ongoing vigilance is required.
Ideal Traits
- Production ownership: Experience shipping, operating, and maintaining ML/LLM systems in production.
- Evaluation instinct: History of inventing metrics to measure and improve systems.
- Depth in LLMs: Retrieval, agentic pipelines, targeted fine-tuning, and judgment on the best tool for each job.
- Full-stack proficiency: Python, FastAPI, Docker, AWS; able to take ideas from research to deployed service independently.
- Judgment under ambiguity: Confident decisions amid unknowns; unafraid to be wrong and adjust fast.
- Communication: Strong collaboration and feedback skills; direct and open style preferred.
Benefits
- Health, dental, and vision insurance
- Ground-floor equity opportunity
- Visa sponsorship (O-1, H-1B, TN) available
- Unlimited PTO
- 401(k) with 4% match
- In-office lunches five days a week
- Professional growth stipend
- Relocation support
Compensation
Highly competitive NYC salary: $230,000 to $350,000 depending on experience, seniority, and ownership level. We benchmark against elite startups and major tech firms, with flexibility at the top of the range for exceptional talent.
Visa sponsorship record: Solstice Solutions Inc
Sponsors actively| Fiscal year | H-1B LCAs | USCIS approvals | USCIS denials | PERM |
|---|---|---|---|---|
| FY2026 | 29 | 3 | 0 | — |
| FY2025 | 9 | 40 | 0 | — |
| FY2024 | 77 | 26 | 1 | — |
✔ Solstice Solutions Inc filed 2 H-1B applications for this kind of role (Software Developers) in the period above.
Roles they sponsor most
- data analyst45 LCAs · median $62k
- clinical data analyst25 LCAs · median $62k
- systems consultant13 LCAs · median $74k
- business intelligence analyst8 LCAs · median $59k
- management analyst5 LCAs · median $84k
Which visas can work for this job
Occupation: Software Developers (SOC 15-1252).
- Mentioned in the listing
H-1B
- H-1B cap-exempt employer
Regular cap-subject employer — a new H-1B needs to win the lottery in March (unless you already hold cap-counted H-1B status).
- TN (citizens of Canada and Mexico)
This kind of role may fit the USMCA profession “Computer Systems Analyst (or Engineer, for engineering-degree holders)” — it depends on the actual duties. No lottery, no cap; you need the matching degree or license.
- E-3 (Australia) and H-1B1 (Chile, Singapore)
Same degree requirement as H-1B, but no lottery and a separate quota that is rarely filled.
- O-1 (extraordinary ability)
For candidates with awards, publications, press, a high salary or critical roles at distinguished organizations. No cap, no lottery; the employer files a petition.
- STEM OPT extension (F-1 students)
Requires an E-Verify employer. We didn't find this company in the E-Verify list — ask HR.
Salary vs prevailing wage
Level IV (fully competent)Software Developers · New York-Newark-Jersey City, NY-NJ. Annual prevailing wages set by the Department of Labor (OFLC).
| Level | Prevailing wage | H-1B lottery odds* |
|---|---|---|
| Level I | $109,845 | ~15% |
| Level II | $137,717 | ~31% |
| Level III | $165,589 | ~46% |
| Level IV | $193,461 | ~61% |
This job pays $230,000–$350,000 a year — that's Level IV (fully competent). In the wage-weighted H-1B lottery a Level IV registration gets 4 entries; estimated selection chance about 61% — better than average.
* Odds are DHS projections for the FY2027 wage-weighted lottery (actual results vary by year and employer). Since the FY2027 cap season the H-1B lottery is weighted by wage level: Level I = 1 entry, II = 2, III = 3, IV = 4. The level is set by the offered wage against the prevailing wage for the occupation and worksite. Separately, a $100,000 fee for new H-1B petitions for workers outside the US was announced in 2025; as of September 2026 a federal court ruling keeps it unenforceable while appeals continue — check the current status.
Sources: U.S. Department of Labor OFLC disclosure data (H-1B/H-1B1/E-3 LCA, PERM), OFLC prevailing wage data, USCIS H-1B Employer Data Hub, E-Verify participating employers. Data loaded: LCA FY2024–FY2026, PERM, USCIS Data Hub, OFLC wages; updated 2026-10-03. Employers are matched by name, so records of companies with similar names can occasionally be mixed up. This is general information, not legal advice — talk to an immigration attorney about your case.